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On Topic Discussion 2019 Coronavirus (COVID-19/SARS-CoV-2)

If you don't have a reaction to the third shot, you might ask your doctor if you should get your antibody levels checked. The test they will run will be a quantitative antibody test instead of qualitative test. You may be one of the lucky 15-20% of people who have no reaction to any of the series of shots. Checking your antibody level will give you some peace of mind.

The CDC does not recommend doing this:

Antibody testing is not currently recommended to assess the need for vaccination in an unvaccinated person or to assess for immunity to SARS-CoV-2 following COVID-19 vaccination. Antibody tests currently authorized under an EUA have variable sensitivity, specificity, as well as positive and negative predictive values, and are not authorized for the assessment of immune response in vaccinated people. Furthermore, the serologic correlates of protection have not been established, and antibody testing does not evaluate the cellular immune response, which may also play a role in vaccine-mediated protection.

https://www.cdc.gov/vaccines/covid-...s.html#considerations-pfizer-biontech-moderna
 
The CDC does not recommend doing this:

Antibody testing is not currently recommended to assess the need for vaccination in an unvaccinated person or to assess for immunity to SARS-CoV-2 following COVID-19 vaccination. Antibody tests currently authorized under an EUA have variable sensitivity, specificity, as well as positive and negative predictive values, and are not authorized for the assessment of immune response in vaccinated people. Furthermore, the serologic correlates of protection have not been established, and antibody testing does not evaluate the cellular immune response, which may also play a role in vaccine-mediated protection.

https://www.cdc.gov/vaccines/covid-...s.html#considerations-pfizer-biontech-moderna

The recommendation from the FDA and the CDC is to avoid overwhelming the lab systems with antibody testing of people who are fully vaccinated. In the US, we have about 230 million people who have been vaccinated and we definitely wouldn't want to try to test that number of people when we can assume that the overwhelming majority of them will have sufficient antibody response to the vaccine. The CDC also has the mistaken belief that if people know they have antibodies, they'll use that as an excuse to not wear masks or take reasonable precautions to avoid infection, a supposition that completely ignores the fact that a large number people who are vaccinated are not wearing masks or taking reasonable precautions already.

That said, we are doing studies of people who received the vaccines to assess their antibody levels of "S" neutralizing antibodies. The test is available to anyone by physician order and insurance will usually cover it. For a person who had little/no apparent immune response to the vaccines, I would recommend discussing the anti-S quantitative test with their physician. The test can be ordered through the major lab companies like Quest and LabCorp and the results will come with a disclaimer saying something like, "antibody level that correlates with immunity has not yet been determined".

I try to avoid political opinions in this thread since it's supposed to be a fact-source but I will offer that the CDC has fallen short on testing recommendations throughout this pandemic. The US does not do enough testing- either in identifying people who are infected or in monitoring variants. The FDA and CDC are relying upon the pharmaceutical companies to provide data regarding antibody levels (Pfizer's studies are coming from Israel which has done a much better job in antibody testing).

I recently heard a public health person say, "Well, 99% of the cases in the US are Delta variant". I'm not sure how that statement can be supported since the US only does variant testing about 1.6% of the positive tests.

The US had over 100,000 positive tests yesterday. They will do genotype (variant) testing on less than 2,000 of those tests.

d41586-021-00908-0_19039550.jpg


Well this sucks for africa,

Only 6.6% of Africa's population is vaccinated.
Contact tracing of people who had this new variant (omicron) had traveled from South Africa. South Africa has vaccinated about 25% of their population.

Although, it's a little unfair to associate South Africa for this latest variant when there's a high likelihood that the same variant is circulating in the US, a country which is more likely to spread variants to other countries than South Africa.
 
I try to avoid political opinions in this thread since it's supposed to be a fact-source but I will offer that the CDC has fallen short on testing recommendations throughout this pandemic. The US does not do enough testing- either in identifying people who are infected or in monitoring variants. The FDA and CDC are relying upon the pharmaceutical companies to provide data regarding antibody levels (Pfizer's studies are coming from Israel which has done a much better job in antibody testing).

I recently heard a public health person say, "Well, 99% of the cases in the US are Delta variant". I'm not sure how that statement can be supported since the US only does variant testing about 1.6% of the positive tests.

The US had over 100,000 positive tests yesterday. They will do genotype (variant) testing on less than 2,000 of those tests.

The county here, trying to figure out where cases were coming from after the surge that followed opening up county parks again and people flooded over from the cities, offered free testing to anyone who had traveled outside the county or who had interacted with someone from outside the county, and there were almost no takers. Maybe no one wanted to get a test result that said they were guilty of spreading the virus? But that ship sailed long ago; I haven't heard of testing here except for people who traveled outside the country,
 
The county here, trying to figure out where cases were coming from after the surge that followed opening up county parks again and people flooded over from the cities, offered free testing to anyone who had traveled outside the county or who had interacted with someone from outside the county, and there were almost no takers. Maybe no one wanted to get a test result that said they were guilty of spreading the virus? But that ship sailed long ago; I haven't heard of testing here except for people who traveled outside the country,

Just to give a comparison with other countries that are open. In some countries, all citizens and tourists have to get an assigned tracking code. Where possible, this number is scanned from a barcode on their phones. When you go to a restaurant, nightclub, theater or other public place, you must give your code in order to enter. If someone in that location tests positive, a database search is done and everyone else who was in that location is told to quarantine at home (or at their hotel). A healthcare team is sent to their location to test them. If they test positive, they are treated and put in isolation. The healthcare team monitors to ensure they are remaining in isolation. If someone who has an exposure (even if they test negative) is discovered to have broken quarantine, they are loaded up and taken to a isolation center where they remain until they have completed their quarantine.

Americans have no clue how loose things are here. And most of them have no clue that 100,000 people are testing positive every day and over 1,000 of those people are dying every day. We'll hit a million deaths somewhere around March, 2023.
 
I got the Moderna booster shot a few days ago. It gave me a nasty headache, a fever, and a swollen arm at the injection site. I'm okay now, and happy that I got the shot. I strongly feel that there will be another serious wave of Covid infections as we move through the Holiday season into Winter. Another factor is that people, mostly the unvaccinated, no longer give a damn whether they wear a mask or social distance. Vaccinated people are getting a bit lazy about mask wearing as well. It's important to protect yourself.
You may be more prophetic than you realized, now that a scary Omicron variant has shown up in southern Africa. More than likely the toothpaste is already out of the tube. Omicron is "loaded" with mutations, and nobody knows yet how well it will evade existing vaccines.

Just as with all other meds or injections or vaccines I've ever gotten in at least the past fifty years (and I get flu shots every year without fail), I have never felt any kind of side effect from anything, outside of MINIMAL soreness near the injection. I've even had antibiotics as strong as Levaquin without any side effects. Of my two original jabs (Moderna) and the booster three weeks ago (Pfizer), the most I noticed was a very slight soreness in my arm that was only noticeable IF I THOUGHT ABOUT IT, and very temporary.

I never even had a side effect from the very ill-fated swine flu shot in the late 1970s.
 
Americans have no clue how loose things are here. And most of them have no clue that 100,000 people are testing positive every day and over 1,000 of those people are dying every day. We'll hit a million deaths somewhere around March, 2023.

Some of us are close to enraged at how some stores here are openly ignoring the state mandate for masks, even to the point of employees not wearing them. Transparent barriers at check stands are disappearing as well.

It doesn't help that as of today the county has dropped the outdoor mask mandate in town; IMHO it gives the wrong impression.
 
Some Facebook stupidity for laughs. I sometimes wonder how these people manage to feed themselves.

The cabal are mocking us with Omicron. Micron is a unit of measurement i.e. one millionth of 1 meter or 1/1000th of a millimeter. The size of “virus” is measured in microns as are the effectiveness of filters/facemasks. So Omicron = Zero Micron or No Virus. Hidden in plain sight.
 
Week ending 27-Nov-2021:

Global COVID-19 Weekly Mortality/Morbidity
  • Global Cases reported: 261,231,815 (up from 257,447,558 / 1.5%) - *‬*3,784,257 new cases this week
  • Global Deaths: 5,198,140 (up from 5,149,871) - **48,269 people died this week

US COVID-19 Weekly Mortality/Morbidity
  • Cases reported in the US - 48,202,506 (up from 47,715,238 / 1.0%), 487,268 new cases, 12.9% of world's new cases were in the US
  • Deaths reported in the US - 776,537 deaths, 5,493 deaths this week , 14.9% of the world's deaths this week were in the US

US Vaccination Weekly Stats
  • Approx number of US doses distributed - 572,190,175 (up from 567,081,775 / +5,108,400) - 79.4% US doses have been administered

    Total US residents vaccinated
  • 1st dose: - 231,367,686 (up from 229,837,421 / +1,530,265) - 70.1% of US population
  • 2nd dose: - 196,168,756 (up from 196,128,496 / +40,260) - 59.4% of US population
  • 3rd dose: - 37,499,004 (up from 34,503,462 / +2,995,542) - 19.1% of US population

    US residents over age 5 vaccinated
  • 1st dose: - 231,331,029 (up from 229,801,222 / +1,529,807) - 74.1% of US population > 5 yo
  • 2nd dose: - 196,159,435 (up from 196,119,179 / +40,256) - 62.8% of US population > 5 yo

    US residents over age 12 vaccinated
  • 1st dose: - 227,687,049 (up from 227,091,798 / +595,251) - 80.3% of US population > 12 yo
  • 2nd dose: - 196,024,740 (up from 195,988,302 / +36,438) - 69.1% of US population > 12 yo

    US residents over age 65 vaccinated
  • 1st dose: - 54,796,073 (up from 54,731,466 / +64,607) - % of US population >65 yo
  • 2nd dose: - 47,177,423 (up from 47,282,382 / -104,959) - % of US population >65 yo
  • 3rd dose: - 19,860,865 (up from 18,912,073 / +948,792) - % of US population >65 yo

Coronavirus weekly cases/deaths in active countries (preference to countries with JUB members):
  • US: 48,202,506 (up from 47,715,238 / +487,268 / 1.0%) - 776,537 deaths (+5,493) - avg daily: cases (+69,610) / deaths (+785) - number is lower this week because of Thanksgiving holiday
  • Germany : 5,788,932 (up from 5,382,587 / +406,345 / 7.5%) - 100,895 deaths (+1,813) - avg daily: cases (+58,049) / deaths (+259)
  • UK : 10,165,796 (up from 9,897,197 / +268,599 / 2.7%) - 145,167 deaths (+798) - avg daily: cases (+38,371) / deaths (+114)
  • Russia: 9,403,480 (up from 9,170,898 / +232,582 / 2.5%) - 267,527 deaths (+8,420) - avg daily: cases (+33,226) / deaths (+1,203)
  • Turkey: 8,726,370 (up from 8,552,347 / +174,023 / 2.0%) - 76,233 deaths (+1,386) - avg daily: cases (+24,860) / deaths (+198)
  • France : 7,654,166 (up from 7,497,920 / +156,246 / 2.1%) - 119,818 deaths (+409) - avg daily: cases (+22,321) / deaths (+58)
  • Netherlands : 2,618,592 (up from 2,483,042 / +135,550 / 5.5%) - 19,721 deaths (+310) - avg daily: cases (+19,364) / deaths (+44)
  • Belgium: 1,701,633 (up from 1,581,500 / +120,133 / 7.6%) - 26,840 deaths (+272) - avg daily: cases (+17,162) / deaths (+39)
  • Italy : 4,994,891 (up from 4,925,688 / +69,203 / 1.4%) - 133,627 deaths (+450) - avg daily: cases (+9,886) / deaths (+64)
  • Brazil: 22,076,863 (up from 22,012,150 / +64,713 / 0.3%) - 614,186 deaths (+1,599) - avg daily: cases (+9,245) / deaths (+228)
  • India: 34,572,523 (up from 34,510,413 / +62,110 / 0.2%) - 468,554 deaths (+2,892) - avg daily: cases (+8,873) / deaths (+413)
  • Spain : 5,131,012 (up from 5,080,663 / +50,349 / 1.0%) - 87,955 deaths (+145) - avg daily: cases (+7,193) / deaths (+21)
  • Switzerland : 986,834 (up from 941,218 / +45,616 / 4.8%) - 11,470 deaths (+88) - avg daily: cases (+6,517) / deaths (+13)
  • Iran : 6,108,882 (up from 6,077,438 / +31,444 / 0.5%) - 129,629 deaths (+673) - avg daily: cases (+4,492) / deaths (+96)
  • Ireland: 560,054 (up from 528,964 / +31,090 / 5.9%) - 5,652 deaths (+43) - avg daily: cases (+4,441) / deaths (+6)
  • South Korea : 440,896 (up from 415,425 / +25,471 / 6.1%) - 3,548 deaths (+274) - avg daily: cases (+3,639) / deaths (+39)
  • Mexico: 3,882,792 (up from 3,862,137 / +20,655 / 0.5%) - 293,859 deaths (+1,487) - avg daily: cases (+2,951) / deaths (+212)
  • Canada : 1,792,561 (up from 1,773,185 / +19,376 / 1.1%) - 29,681 deaths (+135) - avg daily: cases (+2,768) / deaths (+19)
  • Columbia: 5,063,177 (up from 5,045,412 / +17,765 / 0.4%) - 128,394 deaths (+340) - avg daily: cases (+2,538) / deaths (+49)
  • Argentina: 5,325,560 (up from 5,314,702 / +10,858 / 0.2%) - 116,517 deaths (+143) - avg daily: cases (+1,551) / deaths (+20)
  • Sweden: 1,198,848 (up from 1,188,735 / +10,113 / 0.9%) - 15,145 deaths (+35) - avg daily: cases (+1,445) / deaths (+5)
  • Australia : 207,984 (up from 198,443 / +9,541 / 4.8%) - 1,994 deaths (+50) - avg daily: cases (+1,363) / deaths (+7)
  • Lebanon: 666,768 (up from 658,467 / +8,301 / 1.3%) - 8,701 deaths (+66) - avg daily: cases (+1,186) / deaths (+9)
  • Israel: 1,342,022 (up from 1,340,435 / +1,587 / 0.1%) - 8,184 deaths (+8) - avg daily: cases (+227) / deaths (+1)
  • New Zealand: 11,261 (up from 9,973 / +1,288 / 12.9%) - 43 deaths (+4) - avg daily: cases (+184) / deaths (+1)
  • Japan: 1,726,418 (up from 1,725,850 / +568 / 0.0%) - 18,354 deaths (+11) - avg daily: cases (+81) / deaths (+2)
 
The other epidemic...

We're starting to get post-mortem analysis from the past year that shows that during the pandemic in the US, there was an increase in overdose deaths. The increase can be linked to fentanyl and carfentanyl adulteration in heroin. There was also increases in methamphetamine overdoses.

It's also another example of how mental health issues get worse during pandemics.

attachment.php



Drug Overdose Deaths in the U.S. Top 100,000 Annually [CDC]
Provisional data from CDC’s National Center for Health Statistics indicate that there were an estimated 100,306 drug overdose deaths in the United States during 12-month period ending in April 2021, an increase of 28.5% from the 78,056 deaths during the same period the year before.

The new data documents that estimated overdose deaths from opioids increased to 75,673 in the 12-month period ending in April 2021, up from 56,064 the year before. Overdose deaths from synthetic opioids (primarily fentanyl) and psychostimulants such as methamphetamine also increased in the 12-month period ending in April 2021. Cocaine deaths also increased, as did deaths from natural and semi-synthetic opioids (such as prescription pain medication).
 
The other epidemic...

We're starting to get post-mortem analysis from the past year that shows that during the pandemic in the US, there was an increase in overdose deaths. The increase can be linked to fentanyl and carfentanyl adulteration in heroin. There was also increases in methamphetamine overdoses.

It's also another example of how mental health issues get worse during pandemics.

attachment.php



Drug Overdose Deaths in the U.S. Top 100,000 Annually [CDC]

Not trying to be cynical but do you think that some of that increase is due to all the stimulus money and unemployment that was handed out? And before anyone that tries to bash my comment, I’ve spent the past 6 years dealing first hand with a heroin addict.
 
Not trying to be cynical but do you think that some of that increase is due to all the stimulus money and unemployment that was handed out? And before anyone that tries to bash my comment, I’ve spent the past 6 years dealing first hand with a heroin addict.

One thing to call out on the graph- it's a measure of overdose deaths. About 75% of the deaths were opioid related.

Honestly, I don't think the problem is an solely an increase in the number of addicts. The problem is that they are not getting the lower-quality heroin that they're used to.

Carfentanil is so potent that it is almost always lethal. If morphine has a potency of "1", heroin would be "2", fentanyl would be "100", carfentanil would would be "10,000".

Many opioid addicts are functional addicts. They have jobs where their addiction isn't as obvious- working in nightclubs, gig workers, day laborers, etc. Unemployment may have removed the need to be functional and the mental health stresses that came with the pandemic exacerbated their addiction. Most sources attribute the increase in deaths to fentanyl and carfentanil.

If you've been dealing with a heroin addict, then you know that it doesn't matter where the money is coming from, as long as it's coming in. They'll stay functional to keep an income to pay for their habit. They'll steal from work, from family or wherever they can. So, being unemployed and getting an unemployment check or a stimulus check is no different from getting a paycheck, working day labor for cash or stealing. Money is money.
 
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